The pathology of osteoclastoma or giant-cell tumour of bone.
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منابع مشابه
Giant cell tumour (osteoclastoma) of the pancreas--an epithelial tumour probably of pancreatic acinar origin.
A case of giant cell tumour of the pancreas has been studied. The light microscopical appearance of the tumour is indistinguishable from osteoclastoma of bone. Electron microscopy of the tumour shows many typical desmosomes between stromal cells. This is strong evidence of its epithelial nature. The cytoplasm of both the osteoclast-like giant cells and stromal cells contain abundant rough endop...
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Giant cell tumour (GCT) is a benign, locally aggressive tumour of the bone that accounts for 5% of primary bone tumours and 21% of benign bone tumours. This tumour more commonly presents as a single (solitary) lesion; however, it may appear with multiple (multicentric) lesions in less than 1% of the cases. According to the literature, 1-9% of solitary GCTs metastasizes to the lung, more commonl...
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TUMOURS characterized by the presence of giant cells are not uncommonly seen in sections from orbital masses. The histologic appearance of osteoclastoma as first described by N6laton (1860) is of tumours consisting essentially of spindle cells, round cells, and multinucleated giant cells with an abundance of nuclei. It is a rare tumour, which until recently had not been differentiated from othe...
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The malignant transformation of conventional giant cell tumor of bone (GCTOB) is rare and usually occurs with irradiation. Here we report two neglected cases of conventional GCTOB with spontaneous malignant transformation at 11 and 16 years after initial diagnosis. In the former case, the patient refused to receive any treatment following the incisional biopsy, and in the latter, the firs...
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ورودعنوان ژورنال:
- The Journal of bone and joint surgery. British volume
دوره 31B 2 شماره
صفحات -
تاریخ انتشار 1949